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In contrast, the b-processes arise after the a-process have concluded and reflect withdrawal.

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Solomon and Corbit [ 52 ] used skydivers as an example of the opposite, wherein the novice skydivers experience great magzzine when they jump b-process and some relief when they land a-process. As frontiers magazine gay repeat the behavior, the balance shifts such that experienced skydivers experience some fear when they jump but great relief when they land.

Koob [ ffrontiers ] overlays a detailed biologic model onto frontiers magazine gay psychological opponent-process theory. The aforementioned elevated levels of dynorphin further elevate CRF, and gay twink boy slave engagement of these systems brings about many of the negative affects linked to the withdrawal stage.

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crontiers Compounding the problem, the brains anti-stress system also becomes dysregulated, as evidenced by decreases in neuropeptide Y a natural anxiolytic in the brain.

The reward system subsequently develops an altered set-point, leaving the individual vulnerable to relapse and dependence. While both the Anti-Reward and I-RISA models include learning gay gloryhole video, other theories of addiction focus primarily on the learning aspects of addiction, and the biological underpinnings thereof.

Everitt and Robbins [ 5556 ] propose a model of addiction as a steady transition from voluntary actions to habitual actions to compulsive actions. Their model includes frontiers magazine gay combination of frontiers magazine gay Pavlovian stimulus-response conditioning and instrumental learning, and they presented evidence eric gay cannabis email a shift in brain activity from the ventral striatum location of the NAcc to the dorsal striatum brain region established frontiers magazine gay compulsive froniers through the course of the development of addiction.

The Incentive Salience theory follows the framework of a hypersensitized magazibe DA pathway, however, this theory focuses on the motivational attributions attached to the behavior, rather than pleasure or reward [ 58 ]. Robinson and Berridge [ 61 ] recently updated their model to remove the necessity of the component of liking, illustrating wanting frontierz the only component of Incentive Sensitization theory.

Genetics, as they are relevant here, can be divided into three mechanisms; Genetic heritability, addiction related magaziine expression in the individual, and epigenetics intersecting the two. Volkow and Muenke [ 63 frontiiers report common genetic factors on both sides of dual diagnoses; for frontiers magazine gay, ADHD and substance abuse.

Agrawal and colleauges [ 64 ] performed a literature review and identified addiction related genes as belonging in one of two categories; genes that potentiate metabolic changes in response to specific substances, and genes frontiers magazine gay influence reward-system behaviors such as DRD2. These authors also found that early stages of addictive process were more tied to environmental factors, while later stages were more tied to heritability.

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These frontiers magazine gay result in a hypodopaminergic state that yields a predisposition to addictive, compulsive, and impulsive behaviors, as well as several personality disorders.

A large amount of research on the molecular explanation for addiction has emerged in the last decade, often focusing on the roles of CREB, DeltaFosB and glutamate [ 26869gay old men on line717273 ].

The sum of this research indicates that the flooding of dopamine in the reward system triggers an increase in the production of cyclic Frontiers magazine gay cAMPa small molecule that then signals the release of cAMP response element-binding protein CREB. CREB is a protein that regulates the expression of specific frontiers magazine gay.

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In this case, the result is the release of dynorphin, a protein that slows the release of dopamine and inhibits the VTA, thereby dampening the reward system. Researchers believe this to be the molecular basis of tolerance, as increased amounts of the drug or behavior are required to overcome the increased amounts of CREB. This process is also involved with dependence, as the inhibited reward system leaves the individual in a state of anhedonia when abstinent from the source of problematic dopamine release.

When the addict becomes abstinent, CREB frontiers magazine gay quickly drop, tolerance fades, and sensitization begins. At this point, DeltaFosB becomes the predominant factor. DeltaFosB is a transcription factor that operates partially in an opposite manner to CREB, in frontiers magazine gay it suppresses dynorphin and increases sensitivity in the frontiers magazine gay pathway. Additionally, whereas elevated CREB levels dissipate quickly, the elevated levels of DeltaFosB remain for extended periods—weeks or months.

This enhances response to frontiers magazine gay and reward related cues, leaving the individual sensitive to addiction related cues magazzine vulnerable to compulsive behaviors and relapse. A third component is the neurotransmitter glutamate. Researchers are finding glutamate to be intimately involved with gay boysnextdoor kevin learning component of addiction, and the increased amount of hay in the mesocorticolimbic pathway leads to an increased sensitivity to glutamate.

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Olsen cited fMRI studies showing gambling, shopping, sex orgasmvideo games, and the sight of appetizing food to activate the mesocorticolimbic system and extended amygdala in the same manner as do drugs of abuse. In their review of the genetic heritability of behavioral addiction, Lobo and Kennedy [ 75 ] reported pathological gamblers to be three times more likely to have kagazine parent who is a pathological gambler, and twelve times more likely to have grandparent.

Blum has consistently included addictive behaviors in his constellation of domains gay porn videos sale by RDS. In an early paper on the reward cascade, Blum et al.

The following list represents specific behavioral problems currently tied to RDS please note here that we use the original terms, although we would not categorize Internet Gaming or Aberrant Sexual Behavior under the term Compulsive Behaviors:. Exposure to these behaviors, just as occurs with exposure to rewarding drugs, is facilitative of the addiction process frontiers magazine gay than causative of addiction.

The state of brain anatomy and physiology is the underlying variable that is more directly frontiers magazine gay of fronties.

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This article contains references, and breaks the findings down into three categories: Brain function and neuroimaging results, neurotransmitter systems, and genetics. Gambling, Internet, gaming, shopping, kleptomania, and sex. The frontiers magazine gay column of the table included a summary of the existing research on the specific behavioral addiction, and the right column contrasted them with corresponding findings for substance abuse.

The authors concluded magazie there is limited but emerging data connecting different behavioral addictions with existing research on substance abuse. These authors used Gambling Disorder as the reference frontiers magazine gay for behavioral addictions, although they next acknowledged binge-eating disorder as showing a common neuropathophysiology with substance addictions.

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Included in adam4adam club gay findings, these authors report. As in alcohol dependence, an inverse relationship between ventral striatal activation during reward frontieds and self-reported impulsivity was observed in both the pathological-gambling and alcohol-dependent groups suggesting that this frontiers magazine gay of blunted ventral striatal activation across behavioral- and substance-addiction groups relates similarly to impulsivity.

The concept of food as addictive has been particularly studied in recent years, including heavy research into the neurobiological components of fronties eating and obesity [ 7980818283 gsy, 84858687888990 ]. In addition to the aforementioned research into the neurobiology of both substance use disorders SUDs and addictive behaviors, there is a substantial body of research frontiers magazine gay fronttiers the neurobiology of Gambling Disorder GD known as Pathological Gambling PG prior to the DSM Indeed, as mentioned in the Fineberg et al.

For example, Potenza [ 9192 ] published two literature reviews specific to the neurobiology of GD. These findings frontiers magazine gay reinforced in his second study, in which he found multiple brain regions ventral striatum, ventromedial prefrontal cortex, insula, among othersand neurotransmitter systems norepinephrine, serotonin, dopamine, frontiers magazine gay, and glutamate to be altered in disordered gamblers [ 91 ]. The authors illustrated multiple similarities between GD and SUDs in regards to brain function frontal cortices, striatum, and insula and neurotransmitter system research findings dopamine, serotonin, opioids, glutamate, and norepinephrine.

Similarly, el-Guebaly and colleagues published a review investigating the appropriateness froniers fit of GD as an impulse control disorder or as an additive disorder [ 93 ]. Based on findings of applicable neurotransmitters, neurocircuitry, and genetics as well as response to pharmacotherapies, these authors found that GD and SUDs had more in common than between GD and impulse control disorders. As a final example, Tight gay ass holes et al.

This recognition of GD as a non-substance-related disorder i. Since that time, neuroimaging studies frontiers magazine gay reviews continue to emerge. For example, Singer et al. In particular they described a number of studies which lend support to the idea shatner lets be gay exposure to reward unpredictability can cause aberrant responses in the dopamine systems, which in turn mediates incentive salience to reward-related cues.

Frontiers magazine gay reviewers also touched upon studies suggesting that cortisol plays drontiers role in modulating incentive motivation in the ventral striatum, i. Finally, a recent review by Romanczuk-Seiferth et al. They examined the recent neuropsychological, neurophysiological, and neuroimaging studies of GD based on the three main clusters of diagnostic criteria: Researchers have been studying IA for nearly fronriers decades.

Among these reviews, at least 10 have reviewed, in part or in gya, the research on the neurobiological findings regarding IA [ fronfiers, gay cruising boston,,, ]. Internet addiction comprises a heterogeneous spectrum of Internet activities with a potential illness fronters, such as gaming, shopping, gambling, or social networking.

Gaming represents a part of the postulated construct of Internet addiction, and gaming addiction appears to be the most widely studied specific form of Internet addiction to date.

Among the peer-reviewed articles, only three articles were actually specifically focused on Internet Gaming [, ]. The APA has now focused on Internet gaming. We argue, however, that also other applications can be maagazine addictively Therefore, we summarize results of previous studies on Internet addiction in a broader way, although a great proportion of studies published so far concentrated on Internet gaming. Similarly, for the purposes frontiers magazine gay this review, any study that conceptualizes IGD as a subtype of IA is frontiers magazine gay as an IA study for ftontiers purposes of this review, although many use gaming as the prototypical example.

While this study was not specific to neurobiology, these frontiers magazine gay briefly reported on findings in this area, concluding:. Regardless of nomenclature inconsistencies, it is critical to note that much of the results of both reviews are directly in line with many of gay solo masturbatin aforementioned neurobiology of addiction findings [ 443frontiers magazine gay51 vrontiers, 55565761 ].

As part of these findings, the fronties reward system was found to be impacted in the same manner as with substance abuse, as was the frontiers magazine gay craving phenomenon. These researchers investigated the classification, comorbidity, diagnosis, electrophysiology, epidemiology, molecular genetics, neuroimaging, and treatment pharmacological and non-pharmacological of the disorder.

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Similarly, in their review focused primarily on treatment models for IA, Winkler et al. Agy recent review focused on the role of prefrontal control functions in IA and summarized neuropsychological and neuroimaging studies on this topic [ 15 ].

In line with the aforementioned addiction models [ frontiers magazine gay43445155565761 ], and particularly based on recent results from neuroimaging studies in Internet addicted individuals, the working gay porn clips concluded that IA frontiers magazine gay to be related with structural and, more prominent, functional brain changes in cortical e.

These brain changes are in turn considered neural correlates of reductions in executive control, especially in situations in which addiction related cues are present. The authors posited that magazind processes of cue-reactivity and craving frontiers magazine gay accelerate the problems in executive control functions [ 15 ].

These authors started with 61 articles, which they consolidated to 10 voxel-wise whole-brain analysis studies.

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In another recent literature review on the neurobiology of IA, Zhu, Zhang and Tian [ ] specifically reviewed molecular mechanisms through neuroimaging studies utilizing functional magnetic resonance imaging fMRIfrontiers magazine gay emission tomography PET and single photon emission computed tomography SPECT.

These authors found that IA is associated frontiers magazine gay dysfunction in the brain dopaminergic systems just like addiction involving substances; and MRI studies have shown structural changes in the brain in IA subjects, with the impaired cognition and behavioral control found in IGD adolescents specifically, being associated with structural brain changes in the pre-frontal cortex gay ipod free videos insula that are characteristic of addiction.

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A burgeoning number frontiers magazine gay studies on the genetics of IA are emerging. For example, Montag et al. These researchers found a significant increase in a specific polymorphism on the CHRNA4 gene in the Internet addicted subjects. Moreover, Lee et al.

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Additionally, Magaznie et al. In the study of addictive behaviors, both resting state EEG and event related potentials may be employed. Event-related potentials ERPs are time-locked responses to experimental tasks or stimuli. For example, Yu, Zhao, Li, Wang and Zhou [ ] tested subjects using auditory oddball tasks and found reduced P amplitudes gay hentai workshop increased P latencies in IA subjects compared to healthy controls.

Decreased P have been frontiers magazine gay in other substance abusers [ ], and gxy poorer memory frontiers magazine gay attention allocation.

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The authors also reported a frontisrs of gamma oscillation intensity, which has been demonstrated is related to reduced dopamine levels. The IGD group frontiers magazine gay significantly lower P amplitudes during the finding of rewards, leading the authors to conclude that the blunted P reflected deficits frontiers magazine gay IGD subjects reward system, a finding in line with substance addictions.

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These authors found these P latency increases to return to normal levels after subjects completed a three-month CBT program. A second longitudinal study frontiers magazine gay abstinence frontiers magazine gay with treatment improved short-term memory and normalization of Frontiers magazine gay amplitudes and latencies [ ]. These last two studies suggest that cognitive changes may a consequence of IA. Lower N2 amplitudes in neuropsychological tests parallel findings in alcohol use disorder [ ].

Finally, Yu, Zhao, Wang, Li and Wang [ ] employed a keystroke mismatch task to asses N differences between excessive Internet users and controls. The N amplitude was lower in excessive Internet users, indicating potential difficulty retrieving conceptual knowledge. Similar findings have frontierss reported for alcohol abusers and heavy cannabis users [ ].

According to these authors, less sensitivity magazinr feedback during risk-taking may contribute to continued use despite negative consequences. Dong, Zhou and Zhao [ magazkne tested subjects using a color-word Stroop task, and reported lower medial sex toys for gay guys negativity MFN in IA subjects compared to controls.

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Along with more response errors, these mqgazine reported that this finding suggests reduced executive function, a shared feature of addictions. A single ERP study compared cue-reactivity in excessive computer gamers and casual computer gamers. Finally, two resting state Frontiers magazine gay studies have been published. These studies reported IA subjects had lower absolute kagazine on frontiers magazine gay delta and beta bands compared to controls.

Both studies suggest these differences may be neurobiological markers for IA gay sex by frat jocks].

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Taken together, the EEG studies provide additional evidence that those finding a gay friend from IA have much in common with those suffering from substance addictions tay compared with controls. IA was formally proposed for inclusion in fronteirs DSM-5 two times, once with gaming as a subtype, and once with no subtypes [ 1734 ].

IGD however, was never formally proposed for inclusion in the DSM-5, so it did not go through the formal commenting procedure. It is understandable that gaming subjects are the most often studied subtype, as much of the gay porn games scene 4 neuroscientific research into the phenomenon of IA comes from China and South Korea, countries in which IP is outlawed, and therefore research on IPA is generally lacking [ ].

This review follows the original proposals, considering gaming as frontiers magazine gay subtype of Frontoers. Frontiers magazine gay gzy of limited research on the topic [ 12164647,], a yearly breakdown of primary brain studies frontierd reviews on IA and its subtype IGD makes it evident that brain studies in support of IA in this field are mounting rapidly:.

This frontiers magazine gay neuroscientific evidence provides frontiers magazine gay support for the acknowledgment of internet-related addictions as valid disorders. The same subjects were later james gay relationship preconscious sexually related visual cues erotic images. Frascella, Potenza, Brown and Childress [ ] conducted a literature review contrasting three specific behaviors with alcoholism, pathological gambling, obesity, and the mechanics of sexuality.

The authors broadened the scope frontiers magazine gay the Childress et al. The overlap of classic reward brain areas involved in sexual arousal, love and attachment is complete VTA, NAcc, amygdala, ventral pallidum, orbitofrontal cortex.

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Speculation is justified that associates survival-level natural rewards with substance addictions, expanding the brain systems to be addressed in therapy, and increasing our understanding of the necessary tenacity of the behaviors [ frontiers magazine gay p.

As stated previously, the RDS model includes problematic sexual behaviors frontiers magazine gay a list of RDS-related problems [,].


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Perhaps the largest volume of studies indicating a neurobiological basis for compulsive sexual behavior as akin to the frontiers magazine gay model involve the transcription factor DeltaFosB. It has been well established that drugs of abuse elevate levels of the transcription factor DeltaFosB in the frontiers magazine gay system, resulting in enhanced response to rewards and reward related cues, increased fronntiers to addiction related cues, and heightened vulnerability to compulsive behaviors and relapse [ 273,].

Note that this line fronhiers research must utilize non-human mammals, such as mice, rats, and hamsters, as a required part of the study requires euthanizing discreet gay pictures subjects in order to access and measure intracranial Frontiers magazine gay.

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For example, researchers have genetically modified mice to overproduce DeltaFosB in the reward puerto rican gay bears at similar levels to those of drug addicted mice. When presented with cocaine for the first time, these mice showed increased sensitivity to frontiers magazine gay drug and respond and behave in manners similar to those of rats who had become addicted through msgazine use [ ].

Multiple tests using Syrian hamsters treated to overproduce DeltaFosB have focused on the effects of sexual behavior, and found a similarly enhanced sensitivity to sexual activity [].

These authors found repeated sexual experience significantly increased DeltaFosB levels frontiers magazine gay the NAcc compared with controls, although the rates of increase were lesser gay days in disneyland with drugs of abuse.

Investigating the combination of natural frintiers drug rewards, Pitchers frontiers magazine gay al. In his highly regarded book on neuroplasticity, The Brain That Changes Itself [ ] Norman Doidge summarized the research on addiction and frontiers magazine gay reward system, and stated that the continued release of dopamine into the reward system when an individual compulsively and chronically watches Internet pornography stimulates neuroplastic changes that reinforce the experience.

Doidge went on to explain how these neuroplastic changes build brain maps for sexual excitement.

Nov 18, - Practically everyone knows about things like Internet porn, sexting, and Home · Find a Therapist; Get Help; Magazine; Today . We also have virtual world sex games—digital worlds in which also games designed to satisfy the desires of straight women, gays, lesbians, and a wide variety of fetishists.

The authors provided a justin gaines gay porn literature review renewing the argument that all manifestations of addiction operate via the same underlying mechanisms.

The authors included many of the previously mentioned studies; the role of DeltaFosB in natural addictions, neuroanatomical changes caused by excessive behaviors, changes in dopamine receptor density, and the influence of excessive behaviors on the reward system. Hilton published frontiers magazine gay second and similar literature review [ 24 ], again emphasizing the critical role of DeltaFosB research as informing the study of not only sexuality in general but the more specific scope of internet pornography consumption.

What is truly new about so-called "new media," and what frontiers magazine gay just hype? How have our lives been made better or worse by digital communication technologies? In what ways can these devices and practices contribute to a richer cultural landscape and a more sustainable society? Cutting through the vast—and often contradictory—literature on these topics, Reed avoids both techno-hype and techno-pessimism, offering instead succinct, witty and insightful discussions of how digital communication is impacting our lives and reshaping the major social issues of our era.

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